HOME :: Publication > Journal

서브배경라인 TOP 이동 












    Nab-paclitaxel plus gemcitabine versus FOLFIRINOX as the first-line chemotherapy for patients with metastatic pancreatic cancer: retrospective analysis.

    Kang J, Hwang I, Yoo C, Kim KP, Jeong JH, Chang HM, Lee SS, Park DH, Song TJ, Seo DW, Lee SK, Kim MH, Hong SM, Shin SH, Hwang DW, Song KB, Lee JH, Kim SC, Ryoo BY.

    Invest New Drugs. 2018 Apr 3. doi: 10.1007/s10637-018-0598-5. [Epub ahead of print]

    Fusion of a highly N-glycosylated polypeptide increases the expression of ER-localized proteins in plants.

    Kang H, Park Y, Lee Y, Yoo YJ, Hwang I.

    Sci Rep. 2018 Mar 15;8(1):4612. doi: 10.1038/s41598-018-22860-2.

    Physiological and Molecular Processes Associated with Long Duration of ABA Treatment.

    Wang M, Lee J, Choi B, Park Y, Sim HJ, Kim H, Hwang I.

    Front Plant Sci. 2018 Feb 21;9:176. doi: 10.3389/fpls.2018.00176. eCollection 2018.

    Evolution and Design Principles of the Diverse Chloroplast Transit Peptides.

    Lee DW, Hwang I.

    Mol Cells. 2018 Mar 31;41(3):161-167. doi: 10.14348/molcells.2018.0033. Epub 2018 Feb 27. Review.

    AtCAP2 is crucial for lytic vacuole biogenesis during germination by positively regulating vacuolar protein trafficking.

    Kwon Y, Shen J, Lee MH, Geem KR, Jiang L, Hwang I.

    Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1675-E1683. doi: 10.1073/pnas.1717204115. Epub 2018 Jan 29.

    The A/ENTH Domain-Containing Protein AtECA4 Is an Adaptor Protein Involved in Cargo Recycling from the trans-Golgi Network/Early Endosome to the Plasma Membrane.

    Nguyen HH, Lee MH, Song K, Ahn G, Lee J, Hwang I.

    Mol Plant. 2018 Apr 2;11(4):568-583. doi: 10.1016/j.molp.2018.01.001. Epub 2018 Jan 6.

    Prolines in Transit Peptides Are Crucial for Efficient Preprotein Translocation into Chloroplasts.

    Lee DW, Yoo YJ, Razzak MA, Hwang I.

    Plant Physiol. 2018 Jan;176(1):663-677. doi: 10.1104/pp.17.01553. Epub 2017 Nov 20.


    Prolines in Transit Peptides Are Crucial for Efficient Preprotein Translocation into Chloroplasts.

    Lee DW, Yoo YJ, Razzak MA, Hwang I.

    Plant Physiol. 2018 Jan;176(1):663-677. doi: 10.1104/pp.17.01553. Epub 2017 Nov 20.

    Evolution of rubisco complex small subunit transit peptides from algae to plants.

    Razzak MA, Lee DW, Yoo YJ, Hwang I.

    Sci Rep. 2017 Aug 24;7(1):9279. doi: 10.1038/s41598-017-09473-x.

    SCYL2 Genes Are Involved in Clathrin-Mediated Vesicle Trafficking and Essential for Plant Growth.

    Jung JY, Lee DW, Ryu SB, Hwang I, Schachtman DP.

    Plant Physiol. 2017 Sep;175(1):194-209. doi: 10.1104/pp.17.00824. Epub 2017 Jul 27.

    Sorting of nuclear-encoded chloroplast membrane proteins.

    Lee DW, Lee J, Hwang I.

    Curr Opin Plant Biol. 2017 Dec;40:1-7. doi: 10.1016/j.pbi.2017.06.011. Epub 2017 Jun 29. Review.

    SH3 Domain-Containing Protein 2 Plays a Crucial Role at the Step of Membrane Tubulation during Cell Plate Formation.

    Ahn G, Kim H, Kim DH, Hanh H, Yoon Y, Singaram I, Wijesinghe KJ, Johnson KA, Zhuang X, Liang Z, Stahelin RV, Jiang L, Cho W, Kang BH, Hwang I.

    Plant Cell. 2017 Jun;29(6):1388-1405. doi: 10.1105/tpc.17.00108. Epub 2017 Jun 5.

    The Prenylated Rab GTPase Receptor PRA1.F4 Contributes to Protein Exit from the Golgi Apparatus.

    Lee MH, Yoo YJ, Kim DH, Hanh NH, Kwon Y, Hwang I.

    Plant Physiol. 2017 Jul;174(3):1576-1594. doi: 10.1104/pp.17.00466. Epub 2017 May 9.

    Transit peptide elements mediate selective protein targeting to two different types of chloroplasts in the single-cell C4 species Bienertia sinuspersici.

    Wimmer D, Bohnhorst P, Shekhar V, Hwang I, Offermann S.

    Sci Rep. 2017 Jan 23;7:41187. doi: 10.1038/srep41187.


    Nab-paclitaxel plus gemcitabine versus FOLFIRINOX as the first-line chemotherapy for patients with metastatic pancreatic cancer: retrospective analysis.

    Kang J, Hwang I, Yoo C, Kim KP, Jeong JH, Chang HM, Lee SS, Park DH, Song TJ, Seo DW, Lee SK, Kim MH, Hong SM, Shin SH, Hwang DW, Song KB, Lee JH, Kim SC, Ryoo BY.

    Invest New Drugs. 2018 Apr 3. doi: 10.1007/s10637-018-0598-5. [Epub ahead of print]

    Spatial Regulation of ABCG25, an ABA Exporter, Is an Important Component of the Mechanism Controlling Cellular ABA Levels.

    Park Y, Xu ZY, Kim SY, Lee J, Choi B, Lee J, Kim H, Sim HJ, Hwang I.

    Plant Cell. 2016 Oct;28(10):2528-2544. Epub 2016 Oct 3.

    Arabidopsis BAG1 Functions as a Cofactor in Hsc70-Mediated Proteasomal Degradation of Unimported Plastid Proteins.

    Lee DW, Kim SJ, Oh YJ, Choi B, Lee J, Hwang I.

    Mol Plant. 2016 Oct 10;9(10):1428-1431. doi: 10.1016/j.molp.2016.06.005. Epub 2016 Jun 22. No abstract available.

    Interactions between Transmembrane Helices within Monomers of the Aquaporin AtPIP2;1 Play a Crucial Role in Tetramer Formation.

    Yoo YJ, Lee HK, Han W, Kim DH, Lee MH, Jeon J, Lee DW, Lee J, Lee Y, Lee J, Kim JS, Cho Y, Han JK, Hwang I.

    Mol Plant. 2016 Jul 6;9(7):1004-17. doi: 10.1016/j.molp.2016.04.012. Epub 2016 Apr 29.

    Cytochrome b5 Reductase 1 Triggers Serial Reactions that Lead to Iron Uptake in Plants.

    Oh YJ, Kim H, Seo SH, Hwang BG, Chang YS, Lee J, Lee DW, Sohn EJ, Lee SJ, Lee Y, Hwang I.

    Mol Plant. 2016 Apr 4;9(4):501-13. doi: 10.1016/j.molp.2015.12.010. Epub 2015 Dec 19.


    Cytochrome b5 Reductase 1 Triggers Serial Reactions that Lead to Iron Uptake in Plants.

    Oh YJ, Kim H, Seo SH, Hwang BG, Chang YS, Lee J, Lee DW, Sohn EJ, Lee SJ, Lee Y, Hwang I.

    Mol Plant. 2016 Apr 4;9(4):501-13. doi: 10.1016/j.molp.2015.12.010. Epub 2015 Dec 19.

    Physiological Functions of the COPI Complex in Higher Plants.

    Ahn HK, Kang YW, Lim HM, Hwang I, Pai HS.

    Mol Cells. 2015 Oct;38(10):866-75. doi: 10.14348/molcells.2015.0115. Epub 2015 Oct 2.

    Abscisic acid: biosynthesis, inactivation, homoeostasis and signalling.

    Dong T, Park Y, Hwang I.

    Essays Biochem. 2015;58:29-48. doi: 10.1042/bse0580029. Review.

    Cytosolic targeting factor AKR2A captures chloroplast outer membrane-localized client proteins at the ribosome during translation.

    Kim DH, Lee JE, Xu ZY, Geem KR, Kwon Y, Park JW, Hwang I.

    Nat Commun. 2015 Apr 16;6:6843. doi: 10.1038/ncomms7843.

    Iron nanoparticle-induced activation of plasma membrane H(+)-ATPase promotes stomatal opening in Arabidopsis thaliana.

    Kim JH, Oh Y, Yoon H, Hwang I, Chang YS.

    Environ Sci Technol. 2015 Jan 20;49(2):1113-9. doi: 10.1021/es504375t. Epub 2014 Dec 29.

    Targeting and biogenesis of transporters and channels in chloroplast envelope membranes: Unsolved questions.

    Oh YJ, Hwang I.

    Cell Calcium. 2015 Jul;58(1):122-30. doi: 10.1016/j.ceca.2014.10.012. Epub 2014 Oct 31. Review.

    Oral immunization of haemaggulutinin H5 expressed in plant endoplasmic reticulum with adjuvant saponin protects mice against highly pathogenic avian influenza A virus infection.

    Lee G, Na YJ, Yang BG, Choi JP, Seo YB, Hong CP, Yun CH, Kim DH, Sohn EJ, Kim JH, Sung YC, Kim YK, Jang MH, Hwang I.

    Plant Biotechnol J. 2015 Jan;13(1):62-72. doi: 10.1111/pbi.12235. Epub 2014 Jul 26.


  1. Lee J, Kim DH, Hwang I.(2014)
    Specific targeting of proteins to outer envelope membranes of endosymbiotic organelles, chloroplasts, and mitochondria. Front Plant Sci. 2014 Apr 29;5:173.


  1. Dong T, Hwang I.(2014)
    Contribution of ABA UDP-glucosyltransferases in coordination of ABA biosynthesis and catabolism for ABA homeostasis. Plant Signal Behav. 2014 Apr 29;9.


  1. Dong T, Xu ZY, Park Y, Kim DH, Lee Y, Hwang I.(2014)
    Abscisic acid uridine diphosphate glucosyltransferases play a crucial role in abscisic acid homeostasis in Arabidopsis. Plant Physiol. 2014 May;165(1):277-89.


  1. Kim Y, Lee G, Jeon E, Sohn EJ, Lee Y, Kang H, Lee DW, Kim DH, Hwang I. (2014)
    The immediate upstream region of the 5'-UTR from the AUG start codon has a pronounced effect on the translational efficiency in Arabidopsis thaliana.
     Nucleic Acids Res.  42(1):485-98.


  1. Kim DH, Xu ZY, Hwang I. (2013)
    AtHSP17.8 overexpression in transgenic lettuce gives rise to dehydration and salt stress resistance phenotypes through modulation of ABA-mediated signaling.
     Plant Cell Rep.  Dec;32(12):1953-63.
  2. Xu ZY, Kim SY, Hyeon do Y, Kim DH, Dong T, Park Y, Jin JB, Joo SH, Kim SK, Hong JC, Hwang D, Hwang I. (2013)
    The Arabidopsis NAC Transcription Factor ANAC096 Cooperates with bZIP-Type Transcription Factors in Dehydration and Osmotic Stress Responses.
     Plant Cell.  Nov;25(11):4708-24.
  3. Kim SY, Xu ZY, Song K, Kim DH, Kang H, Reichardt I, Sohn EJ, Friml J, Juergens G, Hwang I. (2013)
    Adaptor protein complex 2-mediated endocytosis is crucial for male reproductive organ development in Arabidopsis.
     Plant Cell.  Aug;25(8):2970-85.
  4. Park M1, Song K, Reichardt I, Kim H, Mayer U, Stierhof YD, Hwang I, Jürgens G.
  5. Arabidopsis μ-adaptin subunit AP1M of adaptor protein complex 1 mediates late secretory and vacuolar traffic and is required for growth. PNAS. 2013 Jun 18;110(25):10318-23
  7. Xu ZY, Kim DH, Hwang I. (2013)
    ABA homeostasis and signaling involving multiple subcellular compartments and multiple receptors.
     Plant Cell Rep.  Jun;32(6):807-13.
  8. Kim DH, Hwang I. (2013)
    Direct Targeting of Proteins from the Cytosol to Organelles: The ER versus Endosymbiotic Organelles.
     Traffic.  Jun;14(6):613-21.
  9. Lee JY, Sarowar S, Kim HS, Kim H, Hwang I, Kim YJ, Pai HS. (2013)
    Silencing of Nicotiana benthamiana Neuroblastoma-Amplified Gene causes ER stress and cell death.
     BMC Plant Biol.  Apr;13:69.
  10. Lee KH, Park J, Williams DS, Xiong Y, Hwang I, Kang BH. (2013)
    Defective chloroplast development inhibits maintenance of normal levels of abscisic acid in a mutant of the Arabidopsis RH3 DEAD-box protein during early post-germination growth.
     Plant J.  Mar;73(5):720-32.
  11. Min MK, Jang M, Lee M, Lee J, Song K, Lee Y, Choi KY, Robinson DG, Hwang I. (2013)
    Recruitment of Arf1-GDP to Golgi by Glo3p-type ArfGAPs is crucial for golgi maintenance and plant growth.
     Plant Physiol.  Feb;161(2):676-91.
  12. Lee Y, Jang M, Song K, Kang H, Lee MH, Lee DW, Zouhar J, Rojo E, Sohn EJ, Hwang I. (2013)
    Functional identification of sorting receptors involved in trafficking of soluble lytic vacuolar proteins in vegetative cells of Arabidopsis.
     Plant Physiol.  Jan;161(1):121-33.


  1. Kang H, Kim SY, Song K, Sohn EJ, Lee Y, Lee DW, Hara-Nishimura I, Hwang I. (2012)
    Trafficking of vacuolar proteins: the crucial role of Arabidopsis vacuolar protein sorting 29 in recycling vacuolar sorting receptor.
     Plant Cell.  Dec;24(12):5058-73.
  2. Lee S, Lee DW, Yoo YJ, Duncan O, Oh YJ, Lee YJ, Lee G, Whelan J, Hwang I. (2012)
    Mitochondrial targeting of the Arabidopsis F1-ATPase γ-subunit via multiple compensatory and synergistic presequence motifs.
     Plant Cell.  Dec;24(12):5037-57.
  3. Han YJ, Cho KC, Hwang OJ, Choi YS, Shin AY, Hwang I, Kim JI. (2012)
    Overexpression of an Arabidopsis β-glucosidase gene enhances drought resistance with dwarf phenotype in creeping bentgrass.
     Plant Cell Rep.  Sep;31(9):1677-86.
  4. Kim H, Lee SB, Kim HJ, Min MK, Hwang I, Suh MC. (2012)
    Characterization of glycosylphosphatidylinositol-anchored lipid transfer protein 2 (LTPG2) and overlapping function between LTPG/LTPG1 and LTPG2 in cuticular wax export or accumulation in Arabidopsis thaliana.
     Plant Cell Physiol.  Aug;53(8):1391-403.
  5. Song K, Jang M, Kim SY, Lee G, Lee GJ, Kim DH, Lee Y, Cho W, Hwang I. (2012)
    An A/ENTH domain-containing protein functions as an adaptor for clathrin-coated vesicles on the growing cell plate in Arabidopsis root cells.
     Plant Physiol.  Jul;159(3):1013-25.
  6. Xu ZY, Lee KH, Dong T, Jeong JC, Jin JB, Kanno Y, Kim DH, Kim SY, Seo M, Bressan RA, Yun DJ, Hwang I. (2012)
    A vacuolar β-glucosidase homolog that possesses glucose-conjugated abscisic acid hydrolyzing activity plays an important role in osmotic stress responses in Arabidopsis.
     Plant Cell.  May;24(5):2184-99.
  7. Denecke J, Aniento F, Frigerio L, Hawes C, Hwang I, Mathur J, Neuhaus JM, Robinson DG. (2012)
    Secretory Pathway Research: The More Experimental Systems the Better.
     Plant Cell.  24(4):1316-26.
  8. Lee DW, Jung C, Hwang I. (2012)
    Cytosolic events involved in chloroplast protein targeting.
     Biochim Biophys Acta.  1833(2):245-52.
  9. Yi J, Kim SR, Lee DY, Moon S, Lee YS, Jung KH, Hwang I, An G. (2012)
    The rice gene, DEFECTIVE TAPETUM AND MEIOCYTES 1 (DTM1), is required for early tapetum development and meiosis.
     Plant J.  70(2):256-70.


  1. Jung C, Lee GJ, Jang M, Lee M, Lee J, Kang H, Sohn EJ, Hwang I. (2011)
    Identification of sorting motifs of AtβFruct4 for trafficking from the ER to the vacuole through the Golgi and PVC.
     Traffic.  In press.
  2. Lee MH, Jung C, Lee J, Kim SY, Lee Y, Hwang I. (2011)
    An Arabidopsis prenylated Rab acceptor 1 isoform, AtPRA1.B6, displays differential inhibitory effects on anterograde trafficking of proteins at the endoplasmic reticulum.
     Plant Physiol.  157(2):645-58.
  3. Lee DW, Hwang I. (2011)
    Transient expression and analysis of chloroplast proteins in Arabidopsis protoplasts.
     Methods Mol Biol.  774:59-71.
  4. Kim DH, Xu ZY, Na YJ, Yoo YJ, Lee J, Sohn EJ, Hwang I. (2011)
    Small heat shock protein Hsp17.8 functions as an AKR2A cofactor in the targeting of chloroplast outer membrane proteins in Arabidopsis.
     Plant Physiol.  157(1):132-46.
  5. Zwiewka M, Feraru E, Muller B, Hwang I, Feraru MI, Kleine-Vehn J, Weijers D, Friml J. (2011)
    The AP-3 adaptor complex is required for vacuolar function in Arabidopsis.
     Plant Physiol.  21(12):1711-22.
  6. Lee J, Lee H, Kim J, Lee S, Kim DH, Kim S, Hwang I. (2011)
    Both the Hydrophobicity and a Positively Charged Region Flanking the C-Terminal Region of the Transmembrane Domain of Signal-Anchored Proteins Play Critical Roles in Determining Their Targeting Specificity to the Endoplasmic Reticulum or Endosymbiotic Organelles in Arabidopsis Cells.
     Plant Cell.  23(4):1588-607.
  7. Jung CJ, Lee MH, Min MK, Hwang I. (2011)
    Localization and Trafficking of an Isoform of the AtPRA1 Family to the Golgi Apparatus Depend on Both N- and C-Terminal Sequence Motifs.
     Traffic.  12(2):185-200.


  1. Zhao Y, Yan A, Feij? JA, Furutani M, Takenawa T, Hwang I, Fu Y, Yang Z.(2010)
    Phosphoinositides regulate clathrin-dependent endocytosis at the tip of pollen tubes in Arabidopsis and tobacco.
     Plant Cell.  22(12):4031-44.
  2. Dong CH, Jang M, Scharein B, Malach A, Rivarola M, Liesch J, Groth G, Hwang I, Chang C. (2010)
    Molecular association of the Arabidopsis ETR1 ethylene receptor and a regulator of ethylene signaling, RTE1.
     J Biol Chem.  285(52):40706-13.
  3. Kim H, Kang H, Jang M, Chang JH, Miao Y, Jiang L, Hwang I. (2010)
    Homomeric interaction of AtVSR1 is essential for its function as a vacuolar sorting receptor.
     Plant Physiol.  154(1):134-48
  4. Kim MJ, Go YS, Lee SB, Kim YS, Shin JS, Min MK, Hwang I, Suh MC. (2010)
    Seed-expressed casein kinase I acts as a positive regulator of the SeFAD2 promoter via phosphorylation of the SebHLH transcription factor.
     Plant Mol Biol.  73(4-5):425-37


  1. Lee S, Lee DW, Lee Y, Mayer U, Stierhof YD, Lee S, Jurgens G, Hwang I. (2009)
    Heat Shock Protein Cognate 70-4 and an E3 Ubiquitin Ligase, CHIP, Mediate Plastid-Destined Precursor Degradation through the Ubiquitin-26S Proteasome System in Arabidopsis.
     Plant Cell.  21(12):3984-4001
  2. Jeon Y, Hwang AR, Hwang I, Pai HS. (2009)
    Silencing of NbCEP1 encoding a chloroplast envelope protein containing 15 leucine-rich-repeats disrupts chloroplast biogenesis in Nicotiana benthamiana.
     Mol Cells.  29(2):175-83
  3. Hwang I, Robinson DG. (2009)
    Transport vesicle formation in plant cells.
     Curr Opin Plant Biol.  12(6):660-9
  4. Lee DW, Lee S, Oh YJ, Hwang I. (2009)
    Multiple sequence motifs in the RbcS transit peptide independently contribute to Toc159-dependent import of proteins into chloroplasts.
     Plant Physiol.  151(1):129-41
  5. Kikuchi S, Oishi M, Hirabayashi Y, Lee DW, Hwang I, Nakai M. (2009)
    A 1-Megadalton Translocation Complex Containing Tic20 and Tic21 Mediates Chloroplast Protein Import at the Inner Envelope Membrane.
     Plant Cell.  21(6):1781-97
  6. Agne B, Infanger S, Wang F, Hofstetter V, Rahim G, Martin M, Lee DW, Hwang I, Schnell D, Kessler F. (2009)
    A TOC159 import receptor mutant, defective in hydrolysis of GTP, supports preprotein import into chloroplasts.
     J Biol Chem.  284(13):8670-79
  7. Lee HK, Cho SK, Son O, Xu Z, Hwang I, Kim WT. (2009)
    Drought Stress-Induced Rma1H1, a RING Membrane-Anchor E3 Ubiquitin Ligase Homolog, Regulates Aquaporin Levels via Ubiquitination in Transgenic Arabidopsis Plants.
     Plant Cell.  21:622-41


  1. Hwang I. (2008)
    Sorting and Anterograde Trafficking at the Golgi Apparatus.
    Plant Physiol.  148:673-683
  2. Lee DW, Kim JK, Lee S, Choi S, Kim S, Hwang I. (2008)
    Arabidopsis nuclear-encoded plastid transit peptides contain multiple sequence subgroups with distinctive chloroplast-targeting sequence motifs.
    Plant Cell.  20(6):1603-22
  3. Lee Y, Kim ES, Choi Y, Hwang I, Staiger CJ, Chung YY, Lee Y. (2008)
    The Arabidopsis phosphatidylinositol 3-kinase is important for pollen development.
    Plant Physiol.  147(4):1886-97
  4. Bae WS, Lee YJ, Kim DH, Lee JH, Kim S, Sohn EJ, Hwang I. (2008)
    AKR2A-mediated import of chloroplast outer membrane proteins is essential for chloroplast biogenesis.
    Nat Cell Biol.  10(2):220-227


  1. Dhonukshe P, Aniento F, Hwang I, Robinson DG, Mravec J, Stierhof YD, Friml J. (2007)
    Clathrin-Mediated Constitutive Endocytosis of PIN Auxin Efflux Carriers in Arabidopsis.
     Curr Biol.  17(6):520-527
  2. Min MK, Kim SJ, Miao Y, Shin JY, Jiang L, Hwang I. (2007)
    Overexpression of Arabidopsis AGD7 Causes Relocation of Golgi-localized Proteins to the ER and Inhibits Protein Trafficking in Plant Cells.
     Plant Physiol.  143:1601-1614
  3. Lee GJ, Kim HR, Kang HJ, Jang MH, Lee DW, Lee SJ, Hwang I. (2007)
    EpsinR2 Interacts with Clathrin, AP-3, AtVTI12, and PtdIns(3)P. Implications for EpsinR2 Function in Protein Trafficking in Plant Cells.
     Plant Physiol.  143:1561-1575


  1. Miao Y, Yan PK, Kim HR, Hwang I, Jiang L. (2006)
    Localization of Green Fluorescent Protein Fusions with the Seven Arabidopsis Vacuolar Sorting Receptors to Prevacuolar Compartments in Tobacco BY-2 Cells.
     Plant Physiol. 142:945-962
  2. Lee KH, Piao HL, Kim HY, Choi SM, Jiang F, Hartung W, Hwang I, Kwak JM, Lee IJ, Hwang I. (2006)
    Activation of Glucosidase via Stress-Induced Polymerization Rapidly Increases Active Pools of Abscisic Acid.
     Cell.  126:1109-1120
  3. Song J, Lee MH, Lee GJ, Yoo CM, Hwang I. (2006)
    Arabidopsis EPSIN1 Plays an Important Role in Vacuolar Trafficking of Soluble Cargo Proteins in Plant Cells via Interactions with Clathrin, AP-1, VTI11, and VSR1.
     Plant Cell.  18:2258-2274
  4. Teng YS, Su YS, Chen LJ, Lee YJ, Hwang I, Li HM. (2006)
    Tic21 Is an Essential Translocon Component for Protein Translocation across the Chloroplast Inner Envelope Membrane.
     Plant Cell.  18:2247-2257
  5. Lee DW, Lee S, Lee GJ, Lee KH, Kim S, Cheong GW, Hwang I. (2006)
    Functional characterization of sequence motifs in the transit peptide of Arabidopsis small subunit of rubisco.
     Plant Physiol.  140:466-483
  6. Bae HJ, Lee DS, and Hwang I (2006)
    Dual targeting of xylanase to chloroplasts and peroxisomes as a means to increase protein accumulation in plant cells.
     J Experimental Botany.  57:161-169


  1. Park M, Lee D, Lee GJ, Hwang I. (2005)
    AtRMR1 functions as a cargo receptor for protein trafficking to the protein storage vacuole.
     J Cell Biol.  170:757-767
  2. Joo JH, Yoo HJ, Hwang I, Lee JS, Nam KH, Bae YS (2005)
    Auxin Induced reactive Oxygen species prodution requires the activation of phosphatidylinositol 3-kinase.
     FEBS Letters.  579(5):1243-8
  3. Kim H, Park M, Kim SJ, Hwang I. (2005)
    Actin filaments play a critical role in vacuolar trafficking at the Golgi complex in plant cells.
     Plant Cell.  17(3):888-902
  4. Kim YG, Sohn EJ, Seo J, Lee KJ, Lee HS, Hwang I, Whiteway M, Sacher M, Oh BH. (2005)
    Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP.
     Nat Struct Mol Biol.  12(1):38-45
  5. Lee HY, Bahn SC, Shin JS, Hwang I, Back K, Doelling JH, Ryu SB. (2005)
    Multiple forms of secretory phospholipase A2 in plants.
     Prog Lipid Res.  44(1):52-67


  1. Lee J, Shim D, Song WY, Hwang I, Lee Y. (2004)
    Arabidopsis metallothioneins 2a and 3 enhance resistance to cadmium when expressed in Vicia faba guard cells.
     Plant Mol Biol.  54(6):805-15
  2. Lee GJ, Sohn EJ, Lee MH, Hwang, I. (2004)
    The Arabidopsis Rab5 homelogs Rha1 and Ara7 localize to the prevacuolar compartment.
     Plant Cell Physiology.  45:1211-1220
  3. Song WY, Martinoia E, Lee J, Kim D, Kim DY, Vogt E, Shim D, Choi KS, Hwang I, Lee Y. (2004)
    A novel family of cys-rich membrane proteins mediates cadmium resistance in Arabidopsis.
     Plant Physiol.  135(2):1027-39
  4. Cho HS, Lee SK, Kim DK, Kim SJ, Hwang I, Lim JS, Park YI, Pai, H.S.
    DNA Gyrase Plays a role in DNA Metabolism in Chloroplasts and Mitochondria of Hogher Plants.
     Plant Cell.  16:2665-2682
  5. Lee YJ, Sohn EJ, Lee KH, Lee DW, Hwang, I. (2004)
    The transmembrane domain of AtTco64 and Its C-terminal Lysine-rich Flanking Region Are Targeting Signals to the Chloroplast Outer Envelope Membrane.
     Mol. Cells.  17:281-291
  6. Song WY, Martinoia E, Lee JH, Kim DW, Kim DY, Vogt E, Shim DH, Choi KS, Hwang I, Lee, Y. (2004)
    A novel family of cys-rich membrane proteins mediates cadmium resistance in Arabidopsis.
     Plant Physiology.  135:1027-1039
  7. Lee JH, Shim DH, Song WY, Hwang I, Lee, Y. (2004)
    Arabidopsis metallothioneins 2a and 3 enhance resistance to cadmium when expressed in Vicia faba guard cells.
     Plant Mol. Biology.  54:805-815
  8. Park M, Kim SJ, Vitale A, Hwang I. (2004).
    Identification of the protein storage vacuole and protein targeting to the vacuole in leaf cells of three plant species.
     Plant Physiol.  134:625-639.
  9. Cho CH, Lee CS, Chang M, Jang IH, Kim SJ, Hwang I, Ryu SH, Lee CO, Koh GY. (2004)
    Localization of VEGFR-2 and Phospholipase D2 in Endothelial Caveolae is Involved in VEGF-induced Phosphorylation of MEK and ERK.
     Am J Physiol Heart Circ Physiol
  10. Kim YJ, Kim JE, Lee JH, Lee MH, Jung HW, Bahk YY, Hwang BK, Hwang I, Kim WT. (2004).
    The Vr-PLC3 gene encodes a putative plasma membrane-localized hosphoinositide-specific phospholipase C whose expression is induced by abiotic stress in mung bean (Vigna radiata L.
     FEBS Lett.  556:127-136.


  1. Hong Z, Bednarek SY, Blumwald E, Hwang I, Jurgens G, Menzel D, Osteryoung KW, Raikhel NV, Shinozaki K, Tsutsumi N, Verma DP. (2003).
    A unified nomenclature for Arabidopsis dynamin-related large GTPases based on homology and possible functions.
     Plant Mol Biol.  53:261-265.
  2. Kim CY, Koo YD, Jin JB, Moon BC, Kang CH, Kim ST, Park BO, Lee SY, Kim ML, Hwang I, Kang KY, Bahk JD, Lee SY, Cho MJ.(2003).
    Rice C2-domain proteins are induced and translocated to the plasma membrane in response to a fungal elicitor.
     Biochemistry.  42:11625-11633.
  3. Jin JB, Bae H, Kim SJ, Jin YH, Goh CH, Kim DH, Lee YJ, Tse YC, Jiang L, Hwang I. (2003).
    Arabidopsis dynamin-like proteins, ADL1C and ADL1E, play a critical role in mitochondrial morphogenesis.
     Plant Cell.  15:2357-2369.
  4. Lee KH, Kim SJ, Lee YJ, Jin JB, Hwang I. (2003).
    The M domain of atToc159 plays an essential role in the import of proteins into chloroplasts and chloroplast biogenesis.
     J Biol Chem.  278:36794-36805.
  5. Song WY, Sohn EJ, Martinoia E, Lee YJ, Yang YY, Jasinski M, Forestier C, Hwang I, Lee Y. (2003).
    Engineering tolerance and accumulation of lead and cadmium in transgenic plants.
     Nat Biotechnol.  21:914-919.
  6. Sohn EJ, Kim ES, Zhao M, Kim SJ, Kim H, Kim YW, Lee YJ, Hillmer S, Sohn U, Jiang L, Hwang I. (2003)
    Rha1, an Arabidopsis Rab5 homolog, plays a critical role in the vacuolar trafficking of soluble cargo proteins.
     Plant Cell.  15:1057-1070.
  7. Park KY, Jung JY, Park J, Hwang JU, Kim YW, Hwang I, Lee Y. (2003).
    A role for phosphatidylinositol 3-phosphate in abscisic Acid-induced reactive oxygen species generation in guard cells.
     Plant Physioll.  132:92-98.


  1. Lee, K.H., Kim, D.H., Lee, S.W., Kim, Z.H., and Hwang, I. (2002).
    In vivo Import Experiments in Protoplasts Reveal the Importance of the Ovrall Context but Not Specific Amino Acid Residues of the Transit Peptide during Import into Chloroplasts", Molecules and Cells,14: 388-397.
  2. Jung, J.-Y., Kim, Y.-W., Kwak, J.M., Hwang, J.-U., Young, J., Schroeder, J.I., Hwang, I., and Lee, Y. (2002).
    Phosphatidylinositol 3-and 4-Phosphate Are Required for Normal Stomatal Movements, The Plant Cell, 14: 2399-2412.

  3. Lee, S.H., Jin, J.B., Song, J., Min, M.K., Park, D.S., Kim, Y.-W., and Hwang, I. (2002).
    The Intermolecular Interaction between the PH Domain and the C-terminal Domain of Arabidopsis Dynamin-like 6 Determines Lipid Binding Specificity. The Journal of Biological Chemistry, 277:31842-31849.

  4. Lee, M.H., Min, M.K., Lee, Y.J., Jin, J.B., Shin, D.H., Kim, D.H., Lee, K.-H., and Hwang, I. (2002).
    ADP-Ribosylation Factor 1 of Arabidopsis Plays a Critical Role in Intracellular Trafficking and Maintenance of Endoplasmic Reticulum Morphology in Arabidopsis. Plant Physiology,129:1507-1520.

  5. Kim, D.H., Kim, Y.T., Cho, J.J., Bae, J.H., Hur, S.B., Hwang, I., and Choi, T.J. (2002).
    Stable integration and functional expression of flounder growth hormone gene in transformed microalga, chlorella ellipsoidea. MARINE BIOTECHNOLOGY, 4:63-73.



  1. Kim, Y.-W., Park, D.S., Park, S.-C., Kim, S.H., Cheong, G.-W., and Hwang, I. (2001).
    Arabidopsis Dynamin-Like 2 That Binds Specifically to Phosphatidylinositol 4-Phosphate Assembles into a High-Molecular Weight Complex in Vivo and in Vitro. Plant Physiology, 127:1243-1255.

  2. Lee, Y.J., Kim, D.H.H., Kim, Y.-W., and Hwang, I. (2001).
    Identification of a Signal That Distinguishes between the Chloroplast Outer Envelope Membrane and the Endomembrane System in Vivo. The Plant Cell, 13: 2175-2190.

  3. Jin, J.B., Kim, Y.A, Kim, S.J., Lee, S.H., Kim, D.H., Cheong, G.-W., and Hwang, I. (2001).
    A New Dynamin-Like Protein, ADL6, Is Involved in Trafficking from the trans-Golgi Network to the Central Vacuole in Arabidopsis. The Plant Cell, 13: 1511-1526.

  4. Cho, H.S., Yoon, G.M., Lee, S.S., Kim, Y.A, Hwang, I., Choi, D., and Pai, H.-S. (2001).
    A novel dual-specificity protein kinase targeted to the chloroplast in tobaccoð", FEBS Letters, 497: 124-130.

  5. Kim, J.H., Hong, J.-A, Pih, K.T., and Hwang, I. (2001).
    Identification and isolation of differentially expressed genes in osmotically stressed human oral keratinocytes. Archives of Oral Biology, 46: 335-341.

  6. Kim, D.H., Eu, Y.-J., Yoo, C.M., Kim, Y.-W., Pih, K.T., Jin, J.B., Kim, S.J., Stenmark, H., and Hwang, I. (2001).
    Trafficking of Phosphatidylinositol 3-Phosphate from the trans-Golgi Network to the Lumen of the Central Vacuole in Plant Cells", The Plant Cell, 13: 287-301.

  7. Piao, H.L., Lim, J.H., Kim S.J., Cheoing, G.-W., and Hwang, I. (2001).
    Constitutive over-expression of AtGSK1 induces NaCl stress responses in the absence of NaCl stress and results in enhanced NaCl tolerance in Arabidopsis. The Plant Journal, 27: 305-314.


    ~ 2000

  1. Chung, Y.R., Kim, C.H., Hwang I, and Chun, J.S. (2000).
    Paenibacillus koreensis sp.nov.,a new species that produces an iturin-like antifungal compound", Internatinal Journal of Systematic and Evolutionary Microviology, 50: 1495-1500.

  2. Pih, K.T., Yi, M.J., Liang, Y.S., Shin, B.J., Cho, M.J., Hwang, I., and Son, D.Y. (2000).
    Molecular Cloning and Targeting of a Fibrillarin Homolog from Arabidopsis, Plant Physiology, 123: 51-58.

  3. Lim, J.H., Kang, Y.N., Kim, Y.A., Kim, D.H., and Hwang, I. (1999).
    Construction of small binary vectors for Agrobacterium-mediated transformation in plants. J. Plant Biology, 42: 317-320.
  4. Piao, H.L., Pih, K.T., Lim, J.H., Kang, S.G., Jin, J.B., Kim, S.H., and Hwang, I. (1999).
    An Arabidopsis GSK3/shaggy-Like Gene That Complements Yeast Salt Stress-Sensitive Mutants Is Induced by NaCl and Abscisic Acid. Plant Physiology, 119:1527-1534.

  5. Muramoto, T., Kohchi, T., Yokota, A., Hwang, I., and Goodman, H.M. (1999).
    The Arabidopsis Photomorphogenic Mutant hy1 is Deficient in Phytochrome Chromophore Biosynthesis as a Result of a Mutation in a Plastid Heme Oxygenase (1999). The Plant Cell,11: 335-347.

  6. Pih, K.T., V. Kabilan, Lim, J.H., Kang, S.G., Piao, H.L., Jin, J.B., and Hwang, I. (1999).
    Characterization of Two New Channel Protein Genes in Arabidopsis. Mol. Cells , 9: 84-90.

  7. Nam, I.S., Hong, Y.G., Cho, M.J., Pak, Y.B., and Hwang I., (1999).
    Characterization of Phospholipid and Fatty Acid Composition in the Amp 1-4 Mutant Compared to Wild-Type Arabidopsis thaliana. Journal of Biochemistry and Molecular Biology, 32: 6-11.
  8. Kang, S.G., Jin, J.B., Pai,H.L., Pih, K.T., Jang, H.J.,Lim, J.H., and Hwang, I. (1998).
    Molecular cloning of an Arabidopsis cDNA encoding a dynamin-like protein that is localized to plastids. Plant Mol Biology, 38: 437-447.

  9. Jang, H.J., Pih, K.T., Kang, S.G., Lim, J.H., Jin, J.B., Piao, H.L., and Hwang, I. (1998).
    Molecular cloning of a novel Ca2+-binding protein that is induced by NaCl stress. Plant Mol Biology, 37: 839-847.

  10. Park, J.M., Cho, J.H., Kang, S.G., Jang, H.J., Pih, K.T., Piao, H.L., Cho, M.J., and Hwang, I. (1998).
    A dynamin-like protein in Arabidopsis thaliana is involved in biogenesis of thylakoid membranes. The EMBO Journal, 16: 859-867.

  11. Cheon, H.M., Hwang I, Chungm D,H,, and Seo, S.J. (1998).
    Sequence Analysis and Expression of Met-rich Storage Protein SP-1 of Hyphantria Cunea. Mol. Cells, 8: 219-225.