Postech
MNP Laboratory
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Research Area

Our lab consists of two teams that are focused on different projects.


One of the teams’ main interest is based on the mechanistic roles of VRK1, VRK2, and VRK3, the isoforms of Vaccinia-related kinases (VRKs). We revealed that VRK 1 is involed in the Cell cyle progression, and Memory dysfunction. The functions of VRK 2 are determined being related to Neurodegenerative disease and Schizophrenia, and the roles of VRK3 are ERK signaling regulation, Neurite outgrowth, Kinase activity, and Autism-like behavior, which we were strived to clarify.


The other teams’ main concern is mechanistic regulation of RNA, post-transcriptional regulation. Our study about circadian rhythm for several years elucidated PTB, hnRNP Q, hnRNP R, hnRNP K, hnRNP A1…,  RNA binding proteins controlled clock genes by RNA stability, translation to be fine-control of circadian rhythm. Next, we are eagerly to be clear about the regulating mechanism of local translation of Dendritic mRNA such as Cofilin mRNA by using combined novel molecular techniques. 






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